URINARY CALCULI IN GERMFREE RATS
نویسندگان
چکیده
منابع مشابه
Urinary Calculi in Germfree Rats
In a colony of germfree rats 50 per cent of the males had urinary calculi composed of calcium citrate and calcium oxalate. Genetically closely related conventional animals on the same sterilized diet did not present a single case of stone formation. The tendency to calculus formation disappeared when germfree animals were contaminated with the intestinal flora from conventional rats. The calcul...
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No urobilinogens are present in the feces or urine of germfree rats. After contamination of germfree animals with feces from conventional animals the exgermfree rats produced urobilins to the same extent as conventional animals on the same diet. The negative urobilin test turned positive in germfree animals infected with a single Clostridium-like microorganism isolated from the intestinal conte...
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IJANTITATIVE CHEMICAL ANALYSES of urinary calculi have been done in these laboratories for some twenty years. During this time almost two thousand stones have been examined. In the early days of this period, the only quantitative method available was that of a complete analysis of the inorganic ions and organic compounds present, which was quite difficult and tedious. After the development of t...
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MCNULTY, Mr. P., JR. AND RAFAEL LINARES. Hemorrhagic shock ofgermfree rats. Am. J. Physiol. Ig8( I) : 141-144. 1g6o.Germfree and ordinarv laboratory rats of the same strain, half of each sort treated with oral aureomycin for 3 days prior to shock, were subjected to hemorrhagic shock. At the level and duration of hypotension selected, the procedure was highly lethal for all four groups. The sing...
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Evidence has been provided that a state of irreversible hemorrhagic shock can be induced in a bacteria-free environment in rats reared under germfree conditions. The response to bleeding, the duration of the hypotensive episode and the pathological changes were the same in the germfree and in normal stock rats. The findings are interpreted as evidence opposed to the concept that bacteria or bac...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1962
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.116.3.273